Picking the 5 Best Milk Thistle Supplements

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Milk thistle is a beneficial herbal extract that is often used to help cleanse the liver. Scientific evidence supports the claims about the ability of milk thistle to help protect the liver against the effects of liver disease and hepatitis.

This extract is also a potent antioxidant, which helps to protect the body against oxidative stress and damage from free radicals. There is also evidence that milk thistle possesses anti-inflammatory, as well as antiviral properties. We share the best milk thistle supplements that you are able to get your hands in this post.

Top 5 Milk Thistle Supplements

If you have looked into buying a milk thistle supplement, then you already know just how massive the variety of these products are. After looking at a lot of these supplements, we applied some specific filtering criteria to find the best milk thistle supplements that will give you access to the benefits you expect from this natural extract.

1. aSquared Nutrition Pure Milk Thistle

Asquared Nutrition Pure Milk Thistle

The aSquared Nutrition Pure Milk Thistle Supplement 1000mg is a concentrated formula that aims to give you a quality extract at a great price. Each serving contains 250mg of Milk Thistle extract, but the special extraction method provides a 4x concentrated formula. This means the 250mg serving is equivalent to a 1000mg dose of a standard Milk Thistle extract. Each container offers 200 capsules, with a single capsule needed per serving. This is a vegan-friendly product, and the supplement is produced in a GMP compliant factory within the United States. While the price of the product may seem a little high, consider the fact that taking a single serving each day will provide you with enough pills to last 200 days.


  • 200 capsules in each bottle
  • 4:1 Concentrated extract for improved potency
  • Discounted deals when buying in bulk


  • Even though the product states it is a 1000mg supplement, each serving really contains 250mg, with a 4:1 concentration method.
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2. OmniBiotics Organic Milk Thistle

Omnibiotics Organic Milk Thistle

The OmniBiotics Organic Milk Thistle Supplement gives you a 4X Concentrated product that helps to improve the overall potency of the active compounds in the pill. These supplements are made from organic ingredients, and they are also safe for those who follow a vegan lifestyle. Each serving offers a 1500mg equivalent dose of Milk Thistle extract. The product comes at a price that falls just short of $27 and includes a total of 120 pills. Since each serving size includes a single capsule, this means that buying one container can last you up to 120 days, depending on the number of servings you take per day.


  • 4x Concentrated extraction formula.
  • 120 capsules per container.
  • 100% organic supplement.


  • Higher cost per count compared to some alternatives.
  • Low dosage per pill.
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3. Toniiq Ultra High Strength Milk Thistle

Toniiq Ultra High Strength Milk Thistle

The Toniiq Ultra High Strength Milk Thistle Capsules Supplement is an ideal solution if you require a more potent dose of this extract. This product contains 500mg of Milk Thistle extract in each pill, but the process used in the extraction and production of the supplement gives you a 50:1 concentration ratio. This means that the potency is similar to taking a 25,000mg dose of Milk Thistle. The product has an attractive price of $15.97 per container. You get 90 capsules per bottle, with one capsule providing a full serving. The extraction method used by the manufacturer also helps to improve the bioavailability of the active compounds found in the Milk Thistle extract.


  • One of the most potent formulas on the market
  • Affordable price considering the high dose per serving
  • Made by a reputable brand


  • Capsules contain magnesium stearate
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4. GNC Herbal Plus Milk Thistle

Gnc Herbal Plus Milk Thistle

The GNC Herbal Plus Milk Thistle 1300 MG 60 Caplets supplement is made by a brand that is reputable in the industry. The product offers a 650mg dose of Milk Thistle extract in each capsule, with a 50% Silymarin concentration. This equates to an equivalent of 1300mg standard extract. There are 60 caplets in each bottle. With only one capsule taken per serving, this means a single bottle may last you for up to two months. You have the option to buy a double pack of this supplement, which does give you a reduction in the overall cost per count.


  • 60-day supply per bottle.
  • 1300mg dose of Milk Thistle in each capsule.
  • Bulk-buy option available that gives you the product at a discounted rate.


  • A relatively high cost per serving compared to some of the other supplements.
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5. Fresh Nutrition Milk Thistle

Fresh Nutrition Milk Thistle

One of the major benefits of the Fresh Nutrition Milk Thistle Capsules is the fact that the supplement contains a high Silymarin concentration, rates at 80%. This is much higher than the average Milk Thistle extract supplement. The supplement is available in two different strengths. The latest option from the brand gives you a 10,000mg organic milk thistle extract, with a 20:1 concentration ratio. An alternative option is also available that offers a 2,000mg extract dosage per serving. There is a money-back guarantee that comes with the purchase of this supplement. There are no artificial ingredients added to the supplement, and the product is free of soy and gluten.


  • Potent dose that is equivalent to 10 grams of extracts per serving.
  • 80% Silymarin concentration.
  • It comes with a money-back guarantee.


  • Not the cheapest option when considering the cost per count.
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How We Ranked These Products

When looking at milk thistle supplements, you might be presented with quite a few terms – and these should really be serving as a guide to help you determine which product is right for you. When we looked at the top-rated supplements that contain milk thistle extracts, we considered some essential facts to help us find the ones that are actually worth buying.

Below, we share the most critical elements that we looked at while filtering through the supplements to come up with a list of the five top ones.

Milk Thistle Dose

The first factor we considered is the overall dose that you get with a single serving of each supplement. The dosage is usually indicated in a milligram or gram format. This is the amount of milk thistle extract that you get when you decide to take one of these pills.

A dosage that is low may not give you the benefits that have been associated with the use of Milk Thistle extract, such as an improvement in acne, and to give your liver an extra layer of protection against disease and damage.

You also don’t want a product with a dosage that is too high, however. When the dose is too high, there is a higher risk that you may experience side-effects. The side-effects associated with a high dose of Milk Thistle include diarrhea, an upset stomach, bloating, nausea, and gas.

Silymarin Concentration

We also considered the Silymarin concentration in these supplements an important factor in the process of deciding which ones deserved a spot on our list of the best milk thistle products. The Silymarin concentration tells you how potent the extract is.

Silymarin concentration also refers to the active chemicals that are found in milk thistle, which is linked to the medicinal properties that are linked to the plant. A higher concentration means the actual milk thistle dose can be low, yet you will experience a more potent effect. Some of these products tend to feature quite an impressive concentration of up to 80% Silymarin.


The cost of milk thistle supplements is something else that we considered during our research. When shopping for these supplements, you want to make sure you end up buying a product that will be worth it for the money that you are paying.

We first considered the cost per unit or pill when looking at a product. We then considered the dosage and Silymarin concentration. This allowed us to see which product would give you the most potent concentration of the active chemicals in milk thistle at the best price.

When it comes to the cost, we also considered how long a single bottle of the supplement would last you. Even when a bottle of milk thistle supplements come with 90 or perhaps 120 capsules, there might be smaller bottles that could last for a longer period. Thus, we considered how many capsules should be taken per serving.

While there are some products that only require a single tablet to be taken each day, you will have to take multiple pills per serving with other milk thistle supplements.

Wrapping Up

The use of milk thistle extract has been linked to multiple benefits, ranging from a protective function in the liver, all the way to anti-inflammatory effects that could even be useful for the brain.

There are a lot of these supplements out there, which makes it difficult to find one with the right concentration of the active compounds to benefit you truly.

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