Picking the 5 Best Berberine Supplements

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Berberine is a naturally occurring chemical that has made a name for itself among people who are looking for a herbal remedy to treat diabetes. The chemical is found in a number of different plants, including tree turmeric, Oregon grape, and goldthread.

Berberine has been scientifically proven to reduce insulin resistance and decrease the production of sugar in the liver. Some studies have also shown that berberine might help to speed up weight loss.

While the benefits have been proven, people often find that there are too many berberine supplements available on the market today. This makes it hard to choose a product that will be not only effective but also safe. Which brings you here to us, and this handy guide to buying berberine.

The 5 Best Berberine Supplements

Berberine products have become popular, but not all brands are able to produce the quality that will give you the full benefits of this natural chemical. We looked at the significant variety of berberine supplements that are available right now. We filtered through these products, looking at their potency, while also taking the value provided into account.

Now, let’s go over the five best berberine supplements that you can buy in more detail, shall we?

1. Sunergetic Premium Berberine

Sunergetic Premium Berberine Supplement

The Sunergetic choice gives you a strong 1,200 mg dose of the berberine chemical in every serving, which consists of two capsules. The product does not state the potency of the concentration, however. Each capsule contains a 600 mg dose of the chemical.

Each bottle comes with a 30-day supply of the supplement, providing a total of 60 capsules. The product is manufactured according to the strict guidelines set by the GMP. This is also a non-GMO supplement, which is something that is becoming increasingly important.

The product does not contain artificial ingredients and preservatives and the manufacturer is also dedicated to providing top-quality products. Oregon grape and goldenseal are the two plants used to extract high-quality berberine chemicals.


  • 1,200 mg dose of berberine in every serving.
  • Sixty capsules in each container.
  • Non-GMO supplement.
  • The product is manufactured in a facility that follows GMP standards.
  • Free of soy, corn, gluten, preservatives, and shellfish.


  • Details on concentration purity not provided.
  • Only 30 days of supply per bottle.
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2. Thorne Research Berberine

Thorne Research Berberine 500

The Thorne Research Berberine-500 supplement is a premium product that does come with a high price tag. The company behind the supplement does take care to ensure that every product they bring to the market is made from top-quality ingredients.

The supplement offers 500 mg of berberine in each capsule. Two capsules are advised per serving, providing a dose of one gram. This is a relatively high dosage compared to many of the other berberine supplements out there.

Each bottle comes with 60 capsules. This is an adequate supply for a period of 30 days. The product is free of any ingredients that may not be considered good for the overall health of the body – such as eggs, nuts, barley, sugar, yeast, and corn. There is also no magnesium stearate included in the product, and this is a non-GMO supplement.


  • 500 mg dose of berberine in each capsule.
  • No artificial preservatives used in the formula.
  • Free of genetically modified organisms.
  • It does not use magnesium stearate.


  • A relatively expensive supplement compared to alternatives.
  • Low supply per bottle compared to other options.
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3. Amazing Nutrition Berberine

Amazing Nutrition Berberine Supplement

The Amazing Nutrition Berberine option contains 400 mg dose of the active chemical in every capsule. Each serving consists of a single serving, which means a single bottle of 120 capsules will last you four months. There are larger bottles available if you prefer to buy bulk and save in the process.

The supplement is manufactured in a facility that follows the GMP standards. This provides an overall safer product.

The manufacturer uses a specific form of the active ingredient, known as berberine hydrochloride. The idea behind the use of this ingredient is to enhance the bioavailability of the berberine.


  • 500 mg dose of berberine included in each capsule.
  • Different sized bottles available – up to 360 capsules per container.
  • It is manufactured according to GMP specified standards.
  • It does not contain ingredients that may cause sensitivity reactions.
  • The form of berberine used may improve the absorption of the chemical in your body.


  • The capsules contain gelatin.
  • There is added magnesium stearate included in the supplement.
  • No details provided on the purity of the extract.
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4. Simply Natures Pure Premium Berberine

Simply Natures Pure Premium Berberine

The Simply Natures Pure Premium Berberine option gives you a large number of capsules at a great price. There are 120 capsules in each bottle. The manufacturer claims that a single capsule, providing a dose of 500 mg, is enough on a daily basis.

This choice contains added chromium and cinnamon to add to the health benefits offered by the product. A 100 mcg dose of chromium is supplied per serving, along with 100mg of cinnamon bark extract. It is made in the United States and the capsules are formed to make swallowing easier.


  • 500mg berberine dose per capsule.
  • 120 capsules per bottle.
  • It is produced locally in the US.
  • It contains added chromium and cinnamon.


  • The dose may be too low for some users.
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5. Toniiq Ultra High Strength Berberine

Toniiq Ultra High Strength Berberine

Last up is the Toniiq Ultra High Strength Berberine HCI from the Himalayas. If you are looking for maximum potency, then this is the supplement you want to buy. The product has a high potency, with a 97% standardized purity. The formula also features an 82:1 concentrated extract.

The supplement provides a 500 mg dosage of berberine in each serving. A single serving consists of one capsule. Each bottle of the supplement gives you a 90-day supply.

The product does not contain any additional active ingredients. A vegetable capsule is also used in the production of the capsules. This makes the product ideal for vegetarians. The berberine is produced from foothills that are wild-harvested in the Himalayas to produce a higher-quality and pure product.


  • It only contains berberine HCI as the main active ingredient.
  • It provides an 82:1 concentrated extract.
  • Ninety capsules in each bottle, providing a three-month supply.
  • 500 mg dose of berberine in each capsule.


  • There are more affordable options on the market.
  • It contains silicon dioxide and magnesium stearate.
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How We Ranked These Products

To choose a good berberine supplement, you should not just select a random product and hope it works. There are many options to choose from – and extensive research is needed to make sure the one you buy will give you the benefits associated with the berberine chemical. Take a closer look at the elements we outline below. They will give you an idea of the specific factors that you should consider when looking to buy berberine.

Berberine Dosage

The dosage of berberine included in the supplement is one of the very first things to look at. There are a lot of these products with quite a low dosage of the chemical. In turn, this could make the supplement ineffective. With this in mind, you could end up spending a lot of money on a product that would not give you the benefits you expect.

You should also make sure that the supplement will not provide you with too much of this chemical. There are some side-effects that have been associated with the use of berberine. When the dosage is too strong, you could experience side-effects like constipation, stomach upset, and gas. Some people have also reported diarrhea instead of constipation. Headache is also another common side-effect.

Purity And Concentration

The purity of the supplement is another important factor to consider. It is better to buy a product with a lower dosage that features a high concentration compared to a higher dose with a poor concentration. The concentration tells you how potent the extract used in the supplement is. The concentration will be rated as a percentage. A higher percentage means a more potent formula, which would likely provide you with better results.


You do not want to overspend when buying a berberine supplement. For this reason, take a look at how much value the product offers you. To determine the value of the supplement, you should not only look at its price. Consider the dosage and concentration, how many servings there are in a bottle, and how much each serving would cost you. These are factors that ultimately help you determine which supplement is really worth buying.

Wrapping Up

Berberine might be a useful aid to help you lose weight to reduce insulin resistance, and it could help to improve cholesterol levels. The large variety of supplements can make it confusing to choose one specific product to use. We researched some of the top brands and filtered through them, taking several factors into consideration, to bring you a list of the five best berberine supplements you should consider buying.

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